| Identification | Back Directory | [Name]
N-(Boc-PEG5)-N-bis(PEG4-acid) | [CAS]
2093152-87-3 | [Synonyms]
N-(Boc-PEG5)-N-bis(PEG4-acid) | [Molecular Formula]
C39H76N2O19 | [MDL Number]
MFCD30723283 | [MOL File]
2093152-87-3.mol | [Molecular Weight]
877.02 |
| Hazard Information | Back Directory | [Description]
N-(Boc-PEG5)-N-bis(PEG4-acid) is a branched PEG reagent, it can be conjugated with primary amino groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. Boc protection can be removed under acidic conditions. | [Uses]
N-(Boc-PEG5)-N-bis(PEG4-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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