| Identification | Back Directory | [Name]
Gln-AMS | [CAS]
209543-57-7 | [Synonyms]
Gln-AMS
Adenosine, 5'-[N-[(2S)-2,5-diamino-1,5-dioxopentyl]sulfamate] | [Molecular Formula]
C15H22N8O8S | [MDL Number]
MFCD31746900 | [MOL File]
209543-57-7.mol | [Molecular Weight]
474.45 |
| Chemical Properties | Back Directory | [density ]
2.05±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [form ]
Solid | [pka]
1.21±0.70(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Gln-AMS is an aminoacyl-tRNA synthetases (AARS) inhibitor, which binds the A-domain within the NRPS enzymes. | [References]
[1] Fang P, et al. Structural basis for full-spectrum inhibition of translational functions on a tRNA synthetase. Nat Commun. 2015 Mar 31;6:6402. DOI:10.1038/ncomms7402
[2] Atta-ur-Rahman, et al. Frontiers in Natural Product Chemistry. |
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