| Identification | Back Directory | [Name]
Isotanshinone IIA | [CAS]
20958-15-0 | [Synonyms]
Isotanshinone II
iso-Tanshinone II
Isotanshinone IIA
Isotanshinone II (Salvia miltiorhiza)
1,2,3,4-Tetrahydro-4,4,8-trimethylphenanthro[3,2-b]furan-7,11-dione
Phenanthro[3,2-b]furan-7,11-dione, 1,2,3,4-tetrahydro-4,4,8-trimethyl- | [Molecular Formula]
C19H18O3 | [MDL Number]
MFCD30290650 | [MOL File]
20958-15-0.mol | [Molecular Weight]
294.34 |
| Chemical Properties | Back Directory | [Melting point ]
208 °C | [Boiling point ]
471.1±45.0 °C(Predicted) | [density ]
1.209±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
powder | [color ]
Red |
| Hazard Information | Back Directory | [Uses]
Isotanshinone IIA, an abietane-type diterpene metabolite, could non-competitively inhibit Protein Tyrosine Phosphatase 1B (PTP1B) activity with an IC50 0f 11.4 μM. | [storage]
Store at -20°C | [References]
[1] Han YM, et al. PTP1B inhibitory effect of abietane diterpenes isolated from Salvia miltiorrhiza. Biol Pharm Bull. 2005 Sep;28(9):1795-7. DOI:10.1248/bpb.28.1795 |
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