| Identification | Back Directory | [Name]
Escin, monosodium salt | [CAS]
20977-05-3 | [Synonyms]
Sodium Aescine
Entsufon SodiuM
Sodium escinate
Escin sodium salt
Escin, monosodium salt
Aescin monosodium salt
Escin, Mononatriumsalz
Sodium Aescinate for Injection
Aescin polysulphate sodium salt
Escin, monosodium salt USP/EP/BP | [EINECS(EC#)]
244-133-4 | [Molecular Formula]
C53H82O36S4 | [MDL Number]
MFCD01772116 |
| Safety Data | Back Directory | [Safety Profile]
Poison by ingestion,
intravenous, intraperitoneal, and
subcutaneous routes. Experimental
teratogenic and reproductive effects. When
heated to decomposition it emits toxic
fumes of Na2O. See also SAPONIN and
other escin entries. |
| Hazard Information | Back Directory | [Description]
Escin, monosodium salt is a natural product obtained from the plant horse chestnut. It is used in the treatment of chronic venous insufficiency, where it has been shown to have anti-inflammatory and anti-thrombotic effects. It is a mixture of polysulphated disaccharides that can be purified by HPLC. | [Chemical Properties]
Sodium saponin salt obtained from the extract of the dried mature fruit (Solanum serrata) of the Castanea plant. | [Uses]
Monosodium salt of Escin (E658790), has been used as a treatment for ischemic damage, hemorrhoids, and trauma or for recovery post-operation. Also used in the treatment of adenocarcinoma cell lines. | [in vivo]
Sodium aescinate may effectively controls and improves wound healing in diabetic rats via its anti-inflammatory and antioxidant activities[1].
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Sodium aescinate treatment can alleviate the symptom of polycystic ovary syndrome (PCOS) in rat model through regulating the PI3K/Akt/GSK3-β pathway[4].
| [target]
NO | TNF-α | IL Receptor | Bcl-2/Bax | VEGFR |
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