| Identification | Back Directory | [Name]
GA001 | [CAS]
2097880-27-6 | [Synonyms]
GA001
Benzamide, 3-bromo-N-[2-phenyl-1-(3-phenylpropyl)-1H-benzimidazol-5-yl]- | [Molecular Formula]
C29H24BrN3O | [MOL File]
2097880-27-6.mol | [Molecular Weight]
510.42 |
| Hazard Information | Back Directory | [Uses]
GA001 is a potent G9a antagonist, with an IC50 of 1.32 μM. GA001 induces autophagy and apoptosis that can be used for the breast cancer[1]. | [References]
[1] Zhang J, et al. Synthesis and biological evaluation of benzimidazole derivatives as the G9a Histone Methyltransferase inhibitors that induce autophagy and apoptosis of breast cancer cells. Bioorg Chem. 2017 Jun;72:168-181. DOI:10.1016/j.bioorg.2017.04.005 |
|
|