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2098212-05-4

2098212-05-4 Structure

2098212-05-4 Structure
IdentificationBack Directory
[Name]

8H-Purin-8-one, 2-[3-fluoro-2-(1-methylethyl)phenyl]-7,9-dihydro-9-[[4-[1-methyl-4-(trifluoromethyl)-1H-imidazol-2-yl]phenyl]methyl]-
[CAS]

2098212-05-4
[Synonyms]

USP1-IN-2
2-(3-fluoro-2-propan-2-ylphenyl)-9-[[4-[1-methyl-4-(trifluoromethyl)imidazol-2-yl]phenyl]methyl]-7H-purin-8-one
8H-Purin-8-one, 2-[3-fluoro-2-(1-methylethyl)phenyl]-7,9-dihydro-9-[[4-[1-methyl-4-(trifluoromethyl)-1H-imidazol-2-yl]phenyl]methyl]-
[Molecular Formula]

C26H22F4N6O
[MOL File]

2098212-05-4.mol
[Molecular Weight]

510.49
Chemical PropertiesBack Directory
[density ]

1.41±0.1 g/cm3(Predicted)
[form ]

Solid
[pka]

9.23±0.20(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

USP1-IN-2 (Compound I-193) is a potent ubiquitin-specific protease 1 (USP1) inhibitor with an IC50 of less than about 50 nM[1].
[References]

[1] Alexandre Joseph Buckmelter, et al. Purinones as ubiquitin-specific protease 1 inhibitors. Patent US20170145012A1.
Spectrum DetailBack Directory
[Spectrum Detail]

8H-Purin-8-one, 2-[3-fluoro-2-(1-methylethyl)phenyl]-7,9-dihydro-9-[[4-[1-methyl-4-(trifluoromethyl)-1H-imidazol-2-yl]phenyl]methyl]-(2098212-05-4)1HNMR
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