2098836-50-9

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2098836-50-9 Structure

Chemical Properties	Back Directory
[density ] 1.41±0.1 g/cm3(Predicted)
[storage temp. ] Store at -20°C, protect from light, stored under nitrogen
[solubility ] Soluble in DMSO
[form ] Solid
[pka] 14.05±0.40(Predicted)
[color ] White to off-white

Hazard Information	Back Directory
[Uses] AT6 is a PROTAC AT1 analogue, which is a PROTAC connected by ligands for von Hippel-Lindau and BRD4 with highly selectivity to bromodomain (Brd4).
[References] [1] Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521. DOI:10.1038/nchembio.2329

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