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PCSK9-IN-2 is a novel small molecule inhibitor of PCSK9-LDLR protein–protein interaction (PPI) with an IC50 value of 7.57 μM. | [References]
[1] Sun H, et al. Discovery of Novel Small Molecule Inhibitors Disrupting the PCSK9-LDLR Interaction. J Chem Inf Model. 2021 Oct 25;61(10):5269-5279. DOI:10.1021/acs.jcim.1c00521 |
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