| Identification | Back Directory | [Name]
Benzyloxy carbonyl-PEG3-NHS ester | [CAS]
2100306-68-9 | [Synonyms]
Benzyloxy carbonyl-PEG3-NHS ester | [Molecular Formula]
C21H27NO9 | [MDL Number]
MFCD30723240 | [MOL File]
2100306-68-9.mol | [Molecular Weight]
437.44 |
| Hazard Information | Back Directory | [Description]
Benzyloxy carbonyl-PEG3-NHS ester is a PEG linker which contains a benzyl protecting group and an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The benzyl protecting group can be removed by hydrogenolysis. The PEG linker increases the compounds water solubility in aqueous media. | [Uses]
Benzyloxy carbonyl-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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