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2100306-75-8

2100306-75-8 Structure

2100306-75-8 Structure
IdentificationBack Directory
[Name]

N-(Biotin)-N-bis(PEG1-alcohol)
[CAS]

2100306-75-8
[Synonyms]

Ho-apeg4-oh n-biotin
N-(Biotin)-N-bis(PEG1-alcohol)
[Molecular Formula]

C18H33N3O6S
[MDL Number]

MFCD29912796
[MOL File]

2100306-75-8.mol
[Molecular Weight]

419.54
Chemical PropertiesBack Directory
[Boiling point ]

709.3±60.0 °C(Predicted)
[density ]

1.225±0.06 g/cm3(Predicted)
[pka]

13.90±0.40(Predicted)
Hazard InformationBack Directory
[Description]

N-(Biotin)-N-bis(PEG1-alcohol) is a branched PEG linker with biotin and hydroxyl moieties. The branches are all connected to a central nitrogen atom. The biotin group is used for the conjugation of proteins and can also be used for labeling. The alcohol groups can react to further derivatize the compound.
[Uses]

N-(Biotin)-N-bis(PEG1-alcohol) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[IC 50]

PEGs
[References]

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
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