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2101317-21-7

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2101317-21-7 Structure

2101317-21-7 Structure
IdentificationBack Directory
[Name]

S-GBOXIN
[CAS]

2101317-21-7
[Synonyms]

S-GBOXIN
1H-Benzimidazolium,1-methyl-3-[2-[[(1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl]oxy]-2-oxoethyl]-2-[3-(trifluoromethyl)phenyl]-,iodide(1:1)
[Molecular Formula]

C??H??F?IN?O?
[MDL Number]

MFCD32199204
[MOL File]

2101317-21-7.mol
[Molecular Weight]

600.46
Chemical PropertiesBack Directory
[form ]

Solid
[color ]

White to off-white
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P280-P305+P351+P338
Hazard InformationBack Directory
[Uses]

S-Gboxin is the active analogue of Gboxin; potent antitumor activity.
[in vivo]

S-Gboxin retains excellent metabolic stability, enhanced plasma stability, and PK-properties suitable for in vivo studies. S-Gboxin (10 mg/kg/day; intraperitoneally) inhibits glioblastoma (GBM) growth in vivo[1].

Animal Model:Female nude mice (6 to 9 weeks)[1]
Dosage:10 mg/kg/day
Administration:Administered intraperitoneally; daily; 3 or 14 days
Result:Resulted in significant attenuation of growth and decreased cellular density compared to controls.
Spectrum DetailBack Directory
[Spectrum Detail]

S-GBOXIN(2101317-21-7)1HNMR
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