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2104-68-9

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2104-68-9 Structure

2104-68-9 Structure
IdentificationBack Directory
[Name]

8-CHLOROGUANOSINE
[CAS]

2104-68-9
[Synonyms]

8-CL-GUO
8-Chloroguanoside
8-CHLOROGUANOSINE
8-Chloro-D-guanosine
GUANOSINE, 8-CHLORO-
[Molecular Formula]

C10H12ClN5O5
[MDL Number]

MFCD04118034
[MOL File]

2104-68-9.mol
[Molecular Weight]

317.69
Chemical PropertiesBack Directory
[density ]

2.35±0.1 g/cm3(Predicted)
[pka]

8.41±0.20(Predicted)
Hazard InformationBack Directory
[Uses]

8-Chloroguanosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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