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21052-20-0

21052-20-0 Structure

21052-20-0 Structure
IdentificationBack Directory
[Name]

1-beta-D-Ribofuranosyl-4(1H)-pyrimidinone
[CAS]

21052-20-0
[Synonyms]

4(1H)-Pyrimidinone, 1-β-D-ribofuranosyl-
1-beta-D-Ribofuranosyl-4(1H)-pyrimidinone
1-?β-?D-?ribofuranosyl-4(1H)?-?Pyrimidinone
2-Deoxyuridine, 1-(b-D-ribofuranosyl)-4-pyrimidinone
[Molecular Formula]

C9H12N2O5
[MOL File]

21052-20-0.mol
[Molecular Weight]

228.2
Chemical PropertiesBack Directory
[Boiling point ]

499.0±55.0 °C(Predicted)
[density ]

1.73±0.1 g/cm3(Predicted)
[pka]

12.94±0.70(Predicted)
Hazard InformationBack Directory
[Uses]

2-Deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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