| Identification | Back Directory | [Name]
N-(m-PEG9)-N'-(propargyl-PEG8)-Cy5 | [CAS]
2107273-10-7 | [Synonyms]
N-(m-PEG9)-N'-(propargyl-PEG8)-Cy5
N-(m-PEG9)-N'-(propargyl-PEG8)-Cy5 | [Molecular Formula]
C63H99ClN2O17 | [MDL Number]
MFCD29079417 | [MOL File]
2107273-10-7.mol | [Molecular Weight]
1191.93 |
| Hazard Information | Back Directory | [Uses]
N-(m-PEG9)-N'-(propargyl-PEG8)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-(m-PEG9)-N'-(propargyl-PEG8)-Cy5 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
|
|