| Identification | Back Directory | [Name]
Benzoic acid, 4-[[[(1,1-diMethylethoxy)carbonyl]MethylaMino]Methyl]- | [CAS]
210963-04-5 | [Synonyms]
4-(((tert-Butoxycarbonyl)
4-[[Boc-(methylamino)]methyl]benzoic acid
4-((tert-butoxycarbonyl)Methyl)benzoic acid
4-((tert-butoxycarbonyl(Methyl)aMino)Methyl)benzoic acid
-(((tert-Butoxycarbonyl)(methyl)amino)methyl)benzoic acid
Benzoic acid, 4-[[[(1,1-diMethylethoxy)carbonyl]MethylaMino]Methyl]- | [Molecular Formula]
C14H19NO4 | [MDL Number]
MFCD12844391 | [MOL File]
210963-04-5.mol | [Molecular Weight]
265.3 |
| Chemical Properties | Back Directory | [Boiling point ]
402.9±34.0 °C(Predicted) | [density ]
1.163±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [pka]
4.28±0.10(Predicted) | [Appearance]
White to off-white Solid |
| Hazard Information | Back Directory | [Synthesis]
To a solution of 4-((methylamino)methyl)benzoic acid (compound E1) (2.55 g, 15.4 mmol) in tetrahydrofuran (THF) (93 mL) was sequentially added triethylamine (1.72 g, 17.0 mmol) and di-tert-butyl dicarbonate (Boc2O) (4.04 g, 18.5 mmol). The reaction mixture was stirred at room temperature for 1 h. The target product 4-(((tert-butoxycarbonyl)(methyl)amino)methyl)benzoic acid was purified by fast column chromatography. Yield: 1.5 g (37%), melting point: 131-133 °C. | [References]
[1] Patent: WO2006/589, 2006, A1. Location in patent: Page/Page column 54 |
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| Company Name: |
3A Chemicals
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| Tel: |
400-668-9898 |
| Website: |
www.3achem.com |
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