| Identification | Back Directory | [Name]
ALPROSTADIL ETHANOLAMIDE | [CAS]
210976-81-1 | [Synonyms]
PGE1-EA
ALPROSTADIL ETHANOLAMIDE
PROSTAGLANDIN E1 ETHANOLAMIDE
N-(2-hydroxyethyl)-9-oxo-11α,15S-dihydroxy-prost-13E-en-1-amide
N-(2-HYDROXYETHYL)-9-OXO-11ALPHA,15S-DIHYDROXY-PROST-13E-EN-1-AMIDE
Prost-13-en-1-amide, 11,15-dihydroxy-N-(2-hydroxyethyl)-9-oxo-, (11α,13E,15S)-
N-(2-hydroxyethyl)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]heptanamide | [Molecular Formula]
C22H39NO5 | [MDL Number]
MFCD00797639 | [MOL File]
210976-81-1.mol | [Molecular Weight]
397.55 |
| Chemical Properties | Back Directory | [Boiling point ]
611.9±55.0 °C(Predicted) | [density ]
1.119±0.06 g/cm3(Predicted) | [solubility ]
DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 50 mg/ml; Ethanol:PBS (pH 7.2) (1:1): 0.5 mg/ml; Isotonic Saline: 5 mg/ml | [form ]
A crystalline solid | [pka]
13.85±0.60(Predicted) |
| Hazard Information | Back Directory | [Uses]
Prostaglandin E1 ethanolamide is an analog of prostaglandin E1 (PGE1) and may effectively inhibit GLI2-induced expression of target genes, including Gli1 and Ptch1, and tumor growth[1]. | [Definition]
ChEBI: PGE1-EA is a prostanoid. | [References]
[1] Use of gli2 inhibitor and method for screening compound inhibiting gli2. World Intellectual Property Organization, WO2020182077 A1 2020-09-17. |
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