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Teclistamab is indicated for the treatment of adults with relapsed and refractory multiple myeloma. | [in vivo]
Teclistamab (i.v., 0.1-1 μg, once every 2 days) has anti-tumor activity at high doses in female NSG (NOD/SCID/γc / ) mice with H929 cells model[1].
| Animal Model: | Female NSG mice infected with H929 cell lines[1] | | Dosage: | 0.1 μg (0.005 mg/kg), 0.5 μg (0.025 mg/kg), or 1 μg (0.05 mg/kg) | | Administration: | i.v., on days 0, 3, 5, 7, and 10 | | Result: | Completely inhibited tumor growth at doses of 0.5 and 1 μg, while no inhibition of tumor growth was observed at a dose of 0.1 μg. |
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Biolab Reagents Gold
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027-65279366 18108604356 |
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Shanghai URChem Limited
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http://www.urchem.com |
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Cell Sciences
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9785721070 |
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www.cellsciences.com |
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