ChemicalBook--->CAS DataBase List--->21233-18-1

21233-18-1

21233-18-1 Structure

21233-18-1 Structure
IdentificationBack Directory
[Name]

[(2S,3R,4S,5R,6R)-2-[[(1R,10R)-10-ethenyl-1-hydroxy-5-oxo-4,8-dioxabicyclo[4.4.0]dec-6-en-9-yl]oxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl] 2,4-dihydroxy-6-(3-hydroxyphenyl)benzoate
[CAS]

21233-18-1
[Synonyms]

1H,3H-Pyrano[3,4-c]pyran-1-one, 5-ethenyl-4,4a,5,6-tetrahydro-4a-hydroxy-6-[[2-O-[(3,3',5-trihydroxy[1,1'-biphenyl]-2-yl)carbonyl]-β-D-glucopyranosyl]oxy]-, (4aR,5R,6S)-
[(2S,3R,4S,5R,6R)-2-[[(1R,10R)-10-ethenyl-1-hydroxy-5-oxo-4,8-dioxabicyclo[4.4.0]dec-6-en-9-yl]oxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl] 2,4-dihydroxy-6-(3-hydroxyphenyl)benzoate
[Molecular Formula]

C29H30O14
[MDL Number]

MFCD34471610
[MOL File]

21233-18-1.mol
[Molecular Weight]

602.54
Chemical PropertiesBack Directory
[form ]

Solid
[color ]

Off-white to light yellow
Hazard InformationBack Directory
[Uses]

Amaroswerin is a bioactive secoiridoid glucoside from Swertia mussotii. Amaroswerin has anti-inflammatory, antidiabetic, antiviral, anticholinergic and immunomodulatory activities. Amaroswerin inhibits NO release with an IC50?value of 5.42 μg/mL in?RAW264.7 cells[1].
[Definition]

ChEBI: Amaroswerin is a member of biphenyls.
[References]

[1] Yuan Xiang, et al. Anti-inflammatory activity of compounds isolated from Swertia mussotii. Nat Prod Res. 2019 Feb;33(4):598-601. DOI:10.1080/14786419.2017.1399385
[2] Satyendra Suryawanshi, et al. Assessment of systemic interaction between Swertia chirata extract and its Bioactive constituents in rabbits. Phytother Res. 2009 Jul;23(7):1036-8. DOI:10.1002/ptr.2738
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