| Identification | Back Directory | [Name]
Benzoic acid, 2,4-dihydroxy-6-(3E,5E)-3,5-nonadien-1-yl- | [CAS]
2130080-86-1 | [Synonyms]
Benzoic acid, 2,4-dihydroxy-6-(3E,5E)-3,5-nonadien-1-yl- | [Molecular Formula]
C16H20O4 | [MOL File]
2130080-86-1.mol | [Molecular Weight]
276.33 |
| Hazard Information | Back Directory | [Uses]
SHP2-IN-29 (Compound 3) is a potent SHP2 inhibitor with an IC50 value of 0.18 μM. SHP2-IN-29 also has inhibitory activity against PTP1B and TCPTP, with IC50 values of 4.27 and 4.74 μM, respectively. | [References]
[1] Sun W, et al. Varic acid analogues from fungus as PTP1B inhibitors: Biological evaluation and structure-activity relationships. Bioorg Med Chem Lett. 2017 Aug 1;27(15):3382-3385. DOI:10.1016/j.bmcl.2017.06.001 |
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