| Identification | Back Directory | [Name]
QX-314 | [CAS]
21306-56-9 | [Synonyms]
QX-314
QX-314.Br
QX 314 BROMIDE
LIDOCAINE N-ETHYL BROMIDE
QX-314 - CAS 21306-56-9 - Calbiochem
QX-314 bromide (N-Ethyllidocaine bromide)
LIDOCAINE N-ETHYL BROMIDE (QUATERNARY SALT)
N-(2,6-DIMETHYLPHENYL)ACETAMIDE-2-TRIETHYLAMMONIUM BROMIDE
N-(2,6-DIMETHYLPHENYLCARBAMOYLMETHYL)TRIETHYLAMMONIUM BROMIDE
2-[(2,6-Dimethylphenyl)amino]-N,N,N-triethyl-2-oxoethanaminium
QX-314;LIDOCAINE N-ETHYL BROMIDE;N-(2,6-DIMETHYLPHENYLCARBAMOYLMETHYL)TRIETHYLAMMONIUM BROMIDE | [Molecular Formula]
C16H27N2O+ | [MDL Number]
MFCD00083182 | [MOL File]
21306-56-9.mol | [Molecular Weight]
263.4 |
| Chemical Properties | Back Directory | [Melting point ]
220 - 222°C | [storage temp. ]
Desiccate at RT | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
neat | [color ]
White to Off-White | [Water Solubility ]
water: 3mg/mL | [Concentration]
1 mCi/ml | [Solvent]
Ethanol:water (1:1) | [Specific Activity]
40-60 Ci/mmol |
| Hazard Information | Back Directory | [Uses]
Blocker of voltage-activated sodium channels | [Uses]
QX-314 bromide is a derivative of Lidocaine. It is a local anesthetic. | [Biological Activity]
Membrane impermeable quaternary derivative of lidocaine, a blocker of voltage-activated Na + channels. Intracellular QX 314 bromide also inhibits calcium currents in hippocampal CA1 pyramidal neurons. |
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