| Hazard Information | Back Directory | [Uses]
VCP-Eribulin consists the ADCs linker (VCP) and Eribulin[1]. Eribulin is a mechanistically unique microtubule inhibitor for cancer[2]. VCP-Eribulin is an Eribulin-based agent for antibody conjugates[1]. | [IC 50]
Traditional Cytotoxic Agents | [References]
[1] Earl F Albone, et al. Eribulin-based antibody-drug conjugates and methods of use. US20170252458A1.
[2] Towle MJ, et al. Eribulin induces irreversible mitotic blockade: implications of cell-based pharmacodynamics for in vivo efficacy under intermittent dosing conditions. Cancer Res. 2011 Jan 15;71(2):496-505. DOI:10.1158/0008-5472.CAN-10-1874 |
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Abydos Scientific
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025-84767922 18936879710 |
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http://www.abydoscientific.com/index.html |
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