| Identification | Back Directory | [Name]
2-AMINO-6-TERT-BUTYL-4,5,6,7-TETRAHYDRO-BENZO[B]THIOPHENE-3-CARBOXYLIC ACID METHYL ESTER | [CAS]
213192-26-8 | [Synonyms]
SBB001044
AURORA 12174
AKOS B000469
Oprea1_361075
TimTec1_000538
AK-968/37129027
AKOS BBS-00000802
ART-CHEM-BB B000469
TIMTEC-BB SBB001044
OTAVA-BB BB7111630001
methyl 2-amino-6-tert-butyl-4,5,6,7-tetrahydrobenzothiophene-3-carboxylate
Methyl 2-amino-6-tert-butyl-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate
2-amino-6-tert-butyl-4,5,6,7-tetrahydrobenzothiophene-3-carboxylic acid methyl ester
2-AMINO-6-TERT-BUTYL-4,5,6,7-TETRAHYDRO-BENZO[B]THIOPHENE-3-CARBOXYLIC ACID METHYL ESTER
Benzo[b]thiophene-3-carboxylic acid, 2-amino-6-(1,1-dimethylethyl)-4,5,6,7-tetrahydro-, methyl ester | [Molecular Formula]
C14H21NO2S | [MDL Number]
MFCD01114965 | [MOL File]
213192-26-8.mol | [Molecular Weight]
267.39 |
| Hazard Information | Back Directory | [Uses]
TBTC is a selective agonist with the activity of improving behavioral deficits in Alzheimer's disease model mice. TBTC can effectively activate the heterodimerization of RXRα with LXRα or PPARγ. TBTC stimulates the expression of apoE, ABCA1, and ABCG1 genes and reduces Aβ content in cells and animal models[1]. | [References]
[1] Small molecule TBTC as a new selective retinoid X receptor α agonist improves behavioral deficit in Alzheimer's disease model mice |
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