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213211-10-0

213211-10-0 Structure

213211-10-0 Structure
IdentificationBack Directory
[Name]

BIRT 377
[CAS]

213211-10-0
[Synonyms]

BIRT 377
(5R)-5-[(4-Bromophenyl)methyl]-3-(3,5-dichlorophenyl)-1,5-dimethyl-2,4-imidazolidinedione
[Molecular Formula]

C18H15BrCl2N2O2
[MDL Number]

MFCD28166481
[MOL File]

213211-10-0.mol
[Molecular Weight]

442.13
Chemical PropertiesBack Directory
[Melting point ]

135-136 °C
[Boiling point ]

518.8±60.0 °C(Predicted)
[density ]

1.552±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[form ]

Solid
[pka]

-2.21±0.40(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

BIRT 377 inhibits lymphocyte function-associated antigen-1(LFA-1), which is a cell-adhesion molecule that mediates important immunological events (1). BIRT 377 is also a leukocyte adhesion suppressor (1). Studies showed that BIRT 377 inhibits lymphocyte activity both in vitro and in vivo (2)
[storage]

Store at +4°C
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