| Identification | Back Directory | [Name]
1-METHYLGUANOSINE | [CAS]
2140-65-0 | [Synonyms]
Nsc 70897
1-METHYLGUANOSINE
N1-Methylguanosine
Guanosine, 1-methyl-
RNA-modified nucleoside m1G
Guanosine, 1-methyl- (8ci)(9ci)
1-Methyl-2-amino-9-β-D-ribofuranosyl-9H-purine-6(1H)-one
1-Methyl-2-amino-9-(β-D-ribofuranosyl)-9H-purine-6(1H)-one
2-amino-9-[3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-1-methyl-1,9-dihydropurin-6-one | [Molecular Formula]
C11H15N5O5 | [MDL Number]
MFCD00056011 | [MOL File]
2140-65-0.mol | [Molecular Weight]
297.27 |
| Chemical Properties | Back Directory | [Melting point ]
163 °C | [Boiling point ]
737.4±70.0 °C(Predicted) | [density ]
2.02±0.1 g/cm3(Predicted) | [storage temp. ]
Hygroscopic, -20°C Freezer, Under inert atmosphere | [solubility ]
Methanol (Slightly), Water (Slightly) | [form ]
Solid | [pka]
13.22±0.70(Predicted) | [color ]
White to Off-White | [PH]
～2.4 | [λmax]
258 (pH 1)；256 (pH 6) | [Stability:]
Hygroscopic | [InChI]
InChI=1S/C11H15N5O5/c1-15-9(20)5-8(14-11(15)12)16(3-13-5)10-7(19)6(18)4(2-17)21-10/h3-4,6-7,10,17-19H,2H2,1H3,(H2,12,14)/t4-,6-,7-,10-/m1/s1 | [InChIKey]
UTAIYTHAJQNQDW-KQYNXXCUSA-N | [SMILES]
OC[C@H]1O[C@@H](N2C3=C(C(N(C)C(=N3)N)=O)N=C2)[C@H](O)[C@@H]1O |
| Hazard Information | Back Directory | [Uses]
N1-Methylguanosine-CD3 is the labeled form of N1-Methylguanosine(B426593), which ic use in methods for increasing capping efficiency of transcribed RNA. | [Definition]
ChEBI: Guanosine substituted with a methyl group at position N-1. |
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