2140807-05-0

Directory

2140807-05-0 Structure

Identification	Back Directory
[Name] 2-(5-fluoro-2-hydroxyphenyl)-2-(1-oxo-6-(4-(piperazin-1-yl)phenyl)isoindolin-2-yl)-N-(thiazol-2-yl)acetamide
[CAS] 2140807-05-0
[Synonyms] CPD3616 JBJ-04-125-02 (Rac)-JBJ-04-125-02 2-(5-fluoro-2-hydroxyphenyl)-2-(1-oxo-6-(4-(piperazin-1-yl)phenyl)isoindolin-2-yl)-N-(thiazol-2-yl)acetamide 2H-Isoindole-2-acetamide, α-(5-fluoro-2-hydroxyphenyl)-1,3-dihydro-1-oxo-6-[4-(1-piperazinyl)phenyl]-N-2-thiazolyl-
[Molecular Formula] C29H26FN5O3S
[MOL File] 2140807-05-0.mol
[Molecular Weight] 543.61

Safety Data	Back Directory
[Symbol(GHS) ] GHS07
[Signal word ] Warning
[Hazard statements ] H302-H315-H319-H335
[Precautionary statements ] P261-P280-P301+P312-P302+P352-P305+P351+P338

Hazard Information	Back Directory
[Uses] (Rac)-JBJ-04-125-02 is the racemate of JBJ-04-125-02. JBJ-04-125-02 is a potent, mutant-selective, allosteric and orally active EGFR inhibitor[1].
[IC 50] EGFR (L858R/T790M): 0.26 nM (IC₅₀)
[References] [1] To C, et al. Single and Dual Targeting of Mutant EGFR with an Allosteric Inhibitor. Cancer Discov. 2019 Jul;9(7):926-943. DOI:10.1158/2159-8290.CD-18-0903

Spectrum Detail	Back Directory
[Spectrum Detail] 2-(5-fluoro-2-hydroxyphenyl)-2-(1-oxo-6-(4-(piperazin-1-yl)phenyl)isoindolin-2-yl)-N-(thiazol-2-yl)acetamide(2140807-05-0)¹HNMR

2140807-05-0 suppliers list

Company Name:	Zhejiang J&C Biological Technology Co.,Limited
Tel:	+1-2135480471 +1-2135480471 , +1-2135480471
Website:	https://www.sarms4muscle.com

Company Name:	Nantong HI-FUTURE Biology Co., Ltd.
Tel:	+undefined18051384581 , +undefined18051384581
Website:	https://www.chemhifuture.com/

Company Name:	Guangzhou Tosun Pharmaceutical Limited
Tel:	+8618922120635 , +8618922120635
Website:	toref-standards.com

Company Name:	Wuhan Topule Biopharmaceutical Co., Ltd
Tel:	+8618327326525 , +8618327326525
Website:	topule.com/

Company Name:	Shanghai Topbiochem Technology Co., Ltd
Tel:	021-58170097
Website:	http://www.topbiochem.com

Company Name:	ShangHai Caerulum Pharma Discovery Co., Ltd.
Tel:	18149758185 18149758185
Website:	www.caerulumpharma.com

Company Name:	Shanghai Lollane Biological Technology Co.,Ltd.
Tel:	021-52996696，15000506266 15000506266
Website:	http://www.bioll.com

Company Name:	ATK CHEMICAL COMPANY LIMITED
Tel:	021-51619050 13301662590
Website:	www.atkchemical.com

Company Name:	Shanghai Rechem science Co., Ltd.
Tel:	21-31433387 15618786686
Website:	cn.rechemscience.com

Company Name:	Shanghai SuperLan Chemcial Technique Centre
Tel:	021-2022843681 15618226720
Website:	https://www.chemicalbook.com/ShowSupplierProductsList19886/0.htm

Company Name:	Chuzhou KeMail Chemical Technology Co., Ltd
Tel:	0550-5196001 15000891977
Website:	https://www.chemicalbook.com/ShowSupplierProductsList19947/0.htm

Company Name:	Chengdu Saint - Kay Biotechnology Co., Ltd.
Tel:	028-85157043 15882256948
Website:	https://www.chemicalbook.com/ShowSupplierProductsList30701/0.htm

Company Name:	Zhengzhou Acme Chemical Co., Ltd.
Tel:	0371-037163312495,13303845143 13303845143
Website:	http://www.acmechem.cn

Company Name:	ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel:	18818260767
Website:	http://www.chemegen.com

Tags:2140807-05-0 Related Product Information

HomePage | Member Companies | Advertising | Contact us | Previous WebSite | MSDS | CAS Index | CAS DataBase | Privacy | Terms | About Us
All products displayed on this website are only for non-medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.
According to relevant laws and regulations and the regulations of this website, units or individuals who purchase hazardous materials should obtain valid qualifications and qualification conditions.

Login