ChemicalBook--->CAS DataBase List--->2140807-05-0

2140807-05-0

Request For Quotation
2140807-05-0 Structure

2140807-05-0 Structure
IdentificationBack Directory
[Name]

2-(5-fluoro-2-hydroxyphenyl)-2-(1-oxo-6-(4-(piperazin-1-yl)phenyl)isoindolin-2-yl)-N-(thiazol-2-yl)acetamide
[CAS]

2140807-05-0
[Synonyms]

CPD3616
JBJ-04-125-02
(Rac)-JBJ-04-125-02
2-(5-fluoro-2-hydroxyphenyl)-2-(1-oxo-6-(4-(piperazin-1-yl)phenyl)isoindolin-2-yl)-N-(thiazol-2-yl)acetamide
2H-Isoindole-2-acetamide, α-(5-fluoro-2-hydroxyphenyl)-1,3-dihydro-1-oxo-6-[4-(1-piperazinyl)phenyl]-N-2-thiazolyl-
[Molecular Formula]

C29H26FN5O3S
[MOL File]

2140807-05-0.mol
[Molecular Weight]

543.61
Chemical PropertiesBack Directory
[form ]

Solid
[color ]

White to off-white
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P280-P301+P312-P302+P352-P305+P351+P338
Hazard InformationBack Directory
[Uses]

(Rac)-JBJ-04-125-02 is the racemate of JBJ-04-125-02. JBJ-04-125-02 is a potent, mutant-selective, allosteric and orally active EGFR inhibitor[1].
[IC 50]

EGFR (L858R/T790M): 0.26 nM (IC50)
[References]

[1] To C, et al. Single and Dual Targeting of Mutant EGFR with an Allosteric Inhibitor. Cancer Discov. 2019 Jul;9(7):926-943. DOI:10.1158/2159-8290.CD-18-0903
Spectrum DetailBack Directory
[Spectrum Detail]

2-(5-fluoro-2-hydroxyphenyl)-2-(1-oxo-6-(4-(piperazin-1-yl)phenyl)isoindolin-2-yl)-N-(thiazol-2-yl)acetamide(2140807-05-0)1HNMR
2140807-05-0 suppliers list
Company Name: Zhejiang J&C Biological Technology Co.,Limited
Tel: +1-2135480471 +1-2135480471; , +1-2135480471;
Website: https://www.sarms4muscle.com
Company Name: Nantong HI-FUTURE Biology Co., Ltd.
Tel: +undefined18051384581 , +undefined18051384581
Website: https://www.chemhifuture.com/
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354;
Website: https://www.targetmol.com/
Company Name: Guangzhou Tosun Pharmaceutical Limited
Tel: +86-18124244216 +86-18124244216 , +86-18124244216
Website: http://toref-standards.com
Company Name: Wuhan Topule Biopharmaceutical Co., Ltd
Tel: +8618327326525 , +8618327326525
Website: topule.com/
Company Name: Zibo Hangyu Biotechnology Development Co., Ltd
Tel: +86-0533-2185556 +8615965530500 , +8615965530500
Website: www.chemicalbook.com/manufacturer/hangyu-chemical-25178/
Company Name: Aladdin Scientific
Tel:
Website: www.aladdinsci.com/
Company Name: Shanghai SuperLan Chemcial Technique Centre  Gold
Tel: 0-2022843681 15618226720
Website: www.chemicalbook.com/showsupplierproductslist19886/0_en.htm
Company Name: BOC Sciences  
Tel: 1-631-485-4226; 16314854226
Website: https://www.bocsci.com
Company Name: Shanghai Topbiochem Technology Co., Ltd  
Tel: 021-58170097 15801866362;
Website: http://www.topbiochem.com
Company Name: ShangHai Caerulum Pharma Discovery Co., Ltd.  
Tel: 18149758185 18149758185;
Website: http://www.caerulumpharma.com
Company Name: Hangzhou J&H Chemical Co., Ltd.  
Tel: 0571-87396432
Website: www.jhechem.com
Company Name: Shanghai Lollane Biological Technology Co.,Ltd.  
Tel: 021-52996696，15000506266 15000506266
Website: http://www.bioll.com
Company Name: Shanghai YuanYe Biotechnology Co., Ltd.  
Tel: 021-61312847; 18021002903
Website: http://www.shyuanye.com
Company Name: Shanghai Rechem science Co., Ltd.  
Tel: 021-31433387 15618786686
Website: cn.rechemscience.com
Company Name: Chuzhou KeMail Chemical Technology Co., Ltd  
Tel: 0550-5196001 15000891977
Website: https://www.chemicalbook.com/ShowSupplierProductsList19947/0_EN.htm
Company Name: Chengdu Saint - Kay Biotechnology Co., Ltd.  
Tel: 028-85157043 15882256948
Website: https://www.chemicalbook.com/ShowSupplierProductsList30701/0_EN.htm
Company Name: Zhengzhou Acme Chemical Co., Ltd.  
Tel: 0371-037163312495,13303845143 13303845143
Website: http://www.acmechem.cn
Tags:2140807-05-0 Related Product Information