| Identification | Back Directory | [Name]
BLU-782 | [CAS]
2141955-96-4 | [Synonyms]
BLU-782
ALK2-IN-1
BLU782;BLU 782
(R)-tetrahydrofuran-3-yl 4-(6-(5-(4-ethoxy-1-isopropylpiperidin-4-yl)pyridin-2-yl)pyrrolo[1,2-b]pyridazin-4-yl)piperazine-1-carboxylate
1-Piperazinecarboxylic acid, 4-[6-[5-[4-ethoxy-1-(1-methylethyl)-4-piperidinyl]-2-pyridinyl]pyrrolo[1,2-b]pyridazin-4-yl]-, (3R)-tetrahydro-3-furanyl ester | [Molecular Formula]
C31H42N6O4 | [MOL File]
2141955-96-4.mol | [Molecular Weight]
562.7 |
| Chemical Properties | Back Directory | [storage temp. ]
Sealed in dry,2-8°C | [solubility ]
DMF: insol; DMSO: 1 mg/ml; Ethanol: insol; PBS (pH 7.2): insol | [form ]
A solid | [color ]
Yellow to brown |
| Hazard Information | Back Directory | [Uses]
ALK2-IN-1 is a activin receptor-like kinase-2 (ALK2) inhibitor extracted from patent WO2017181117A1, Compound 876, has an IC50 of <10 nM[1]. | [References]
[1] Natasja Brooijmans, et al. Inhibitors of activin receptor-like kinase. WO2017181117A1. |
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