2141981-88-4

Directory

2141981-88-4 Structure

Identification	Back Directory
[Name] TCO4-PEG3-NHS
[CAS] 2141981-88-4
[Synonyms] TCO4-PEG3-NHS 5,8,11-Trioxa-2-azatetradecanedioic acid, 1-(4-cycloocten-1-yl) 14-(2,5-dioxo-1-pyrrolidinyl) ester
[Molecular Formula] C22H34N2O9
[MDL Number] MFCD31811534
[MOL File] 2141981-88-4.mol
[Molecular Weight] 470.51

Chemical Properties	Back Directory
[density ] 1.24±0.1 g/cm3(Predicted)
[solubility ] Soluble in DMSO, DCM, DMF
[pka] 11.95±0.46(Predicted)

Hazard Information	Back Directory
[Description] TCO-PEG3-NHS Ester is a PEG linker containing a TCO moiety and a NHS ester. The hydrophilic PEG spacer increases water-solubility and a decreases steric hindrance during ligation. This reagent can be used to label antibodies, proteins and other primary amine-containing macromolecules with TCO moiety.
[Uses] TCO-PEG3-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
[IC 50] PEGs
[References] [1] Wang Y, et al. Degradation of proteins by PROTACs and other strategies. Acta Pharm Sin B. 2020 Feb;10(2):207-238. DOI:10.1016/j.apsb.2019.08.001

2141981-88-4 suppliers list

Company Name:	Jilin Chinese Academy of Sciences-yanshen Technology
Tel:	+undefined18143011203 , +undefined18143011203
Website:	www.chemextension.com/

Company Name:	Changzhou Hopschain Chemical Co.,Ltd.
Tel:	0519-85528066 13775048983
Website:	http://www.hopschem.com/

Company Name:	Beijing Jin Ming Biotechnology Co., Ltd.
Tel:	010-60605840 18892239720
Website:	http://www.jm-bio.com/

Company Name:	Shaanxi Xinyan Bomei Biotechnology Co., Ltd.
Tel:	029-86217788 13892832556
Website:	http://www.xinyanbm.com/

Company Name:	Birdo (Shanghai) Medical Technology Co., Ltd.
Tel:	021-58099077-8041 18601625411
Website:	product.birdotech.com/

Company Name:	Taizhou Nanfeng Pharmaceutical Research Institute
Tel:	18616377689
Website:	www.chemicalbook.com/showsupplierproductslist1580880/0.htm

Company Name:	Nanjing Shizhou Biology Technology Co.,Ltd
Tel:	025-85563444 18351873721
Website:	http://www.synzest.com

Company Name:	Nanjing Shizhou Biology Technology Co.,Ltd
Tel:	13675144456
Website:	http://www.synzest.com

Company Name:	Zhengzhou Akem Chemical Co., Ltd
Tel:	13303867194
Website:	http://acmechem.cn/

Company Name:	Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd
Tel:	0431-80514535 19917294565
Website:	www.chemextension.com

Company Name:	Henan Alpha Chemical Co., Ltd.
Tel:	0371-55013243 15324716602
Website:	https://www.chemicalbook.com/supplier/24684125/

Company Name:	Shanghai Zhiyun Biotechnology Co., Ltd
Tel:	13119135307
Website:

Company Name:	Jilin Chinese Academy of Sciences-yanshen Technology
Tel:	18143011203
Website:	http://www.chemextension.com/

Tags:2141981-88-4 Related Product Information

1621096-79-4 2141981-86-2 1802913-21-8 1914971-04-2 1800507-93-0 2141981-85-1

HomePage | Member Companies | Advertising | Contact us | Previous WebSite | MSDS | CAS Index | CAS DataBase | Privacy | Terms | About Us
All products displayed on this website are only for non-medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.
According to relevant laws and regulations and the regulations of this website, units or individuals who purchase hazardous materials should obtain valid qualifications and qualification conditions.

Login