| Identification | Back Directory | [Name]
Benzoic acid, 3-[[2-(4-pentylphenoxy)acetyl]amino]-, methyl ester | [CAS]
2143463-31-2 | [Synonyms]
MDH1-IN-1
Benzoic acid, 3-[[2-(4-pentylphenoxy)acetyl]amino]-, methyl ester | [Molecular Formula]
C21H25NO4 | [MOL File]
2143463-31-2.mol | [Molecular Weight]
355.43 |
| Chemical Properties | Back Directory | [Boiling point ]
549.5±40.0 °C(Predicted) | [density ]
1.142±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
12.95±0.70(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
MDH1-IN-1 (Compound 5i) is a potent inhibitor of MDH1 with an IC50 of 6.79 μM. MDH1-IN-1 has the potential for the research of cancer diseases[1]. | [References]
[1] Naik R, et al. Methyl 3-(3-(4-(2,4,4-Trimethylpentan-2-yl)phenoxy)-propanamido)benzoate as a Novel and Dual Malate Dehydrogenase (MDH) 1/2 Inhibitor Targeting Cancer Metabolism. J Med Chem. 2017;60(20):8631-8646. DOI:10.1021/acs.jmedchem.7b01231 |
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