| Identification | Back Directory | [Name]
Benzoic acid, 4-methoxy-3-[[2-[4-(1,1,3,3-tetramethylbutyl)phenoxy]acetyl]amino]-, methyl ester | [CAS]
2143463-35-6 | [Synonyms]
MDH1-IN-2
Benzoic acid, 4-methoxy-3-[[2-[4-(1,1,3,3-tetramethylbutyl)phenoxy]acetyl]amino]-, methyl ester | [Molecular Formula]
C25H33NO5 | [MOL File]
2143463-35-6.mol | [Molecular Weight]
427.53 |
| Chemical Properties | Back Directory | [Boiling point ]
574.4±50.0 °C(Predicted) | [density ]
1.108±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 25 mg/mL (58.48 mM; Need ultrasonic) | [form ]
Solid | [pka]
12.33±0.70(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
MDH1-IN-2 (Compound 7c) is a potent and selelctive inhibitor of MDH1 with an IC50 of 2.27 μM. MDH1-IN-2 has the potential for the research of cancer diseases[1]. | [storage]
Store at -20°C | [References]
[1] Naik R, et al. Methyl 3-(3-(4-(2,4,4-Trimethylpentan-2-yl)phenoxy)-propanamido)benzoate as a Novel and Dual Malate Dehydrogenase (MDH) 1/2 Inhibitor Targeting Cancer Metabolism. J Med Chem. 2017;60(20):8631-8646. DOI:10.1021/acs.jmedchem.7b01231 |
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