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KUNG65 is a selective inhibitor of Grp94, with a target Kd of 540 nM and at least 73 fold selectivity vs. the other Hsp90 isoforms[1]. | [References]
[1] Kyler Pugh, et al. Investigation of the site 2 pocket of Grp94 with KUNG65 benzamide derivatives. Bioorg Med Chem Lett. 2024 Oct 1:111:129893. DOI:10.1016/j.bmcl.2024.129893 |
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