| Identification | Back Directory | [Name]
5-CHLORO-2-FURALDEHYDE | [CAS]
21508-19-0 | [Synonyms]
EOS-61611
5-Chlorofurfural
TIMTEC-BB SBB004223
5-CHLORO-2-FURALDEHYDE
5-CHLORO-2-FURALDEHYDE,97%
5-Chloro-2-furaldehyde 98%
5-CHLORO-2-FURALDEHYDE, 98+%
5-chlorofuran-2-carbaldehyde
5-Chloro-2-furancarboxaldehyde
5-chlorofuran-2-carboxaldehyde
5-Chloro-2-furaldehyde,97%,stabilized
5-Chloro-2-furaldehyde, stabilized, 97%
5-Chloro-2-furaldehyde, stabilized, 97% 1GR
5-Chloro-2-furaldehyde, 98%, stab. with 2% ethanol
5-Chloro-2-furaldehyde, stabilized with 2% ethanol | [EINECS(EC#)]
-0 | [Molecular Formula]
C5H3ClO2 | [MDL Number]
MFCD02752599 | [MOL File]
21508-19-0.mol | [Molecular Weight]
130.53 |
| Questions And Answer | Back Directory | [Synthesis]
Furfural (30 mmol) and ZnCl₂ (30 mmol) were dissolved in AcOH (30 mL) and stirred at room temperature. After 1 hour, a small amount of substrate (10 mmol) in acetic acid (5 mL) was added. The mixture was stirred at 70°C for 24 hours and diluted with Et₂O (100 mL), and washed successively with 0.1 N Na₂S₂O₃ (50 mL), 0.1 N NaHCO₃ (20 mL), and brine (20 mL). The organic phase was dried (Na₂SO₄) to remove the solvent, yielding a crude product. This crude product was purified by column chromatography or vacuum distillation to obtain 5-CHLORO-2-FURALDEHYDE, in 10% yield. |
| Chemical Properties | Back Directory | [Appearance]
White to yellow powder | [Melting point ]
34-37 °C(lit.)
| [Boiling point ]
70°C 10mm | [density ]
1.361±0.06 g/cm3(Predicted) | [Fp ]
190 °F
| [storage temp. ]
2-8°C | [solubility ]
Acetone (Slightly), Methanol (Slightly) | [form ]
Crystalline Powder | [color ]
White to off-white | [Water Solubility ]
Insoluble in water. | [Sensitive ]
Air Sensitive | [BRN ]
108401 | [Exposure limits]
ACGIH: STEL 1000 ppm
OSHA: TWA 1000 ppm(1900 mg/m3)
NIOSH: IDLH 3300 ppm; TWA 1000 ppm(1900 mg/m3) | [InChI]
1S/C5H3ClO2/c6-5-2-1-4(3-7)8-5/h1-3H | [InChIKey]
DGAUAVDWXYXXGQ-UHFFFAOYSA-N | [SMILES]
Clc1ccc(C=O)o1 |
| Hazard Information | Back Directory | [Chemical Properties]
White to yellow powder | [Uses]
(+)-1-Deoxynojirimycin hydrochloride interferes with normal processing of N-linked glycoproteins, producing reduced amounts of complex type oligosaccharides. | [Uses]
5-Chloro-2-furaldehyde may be used as an internal standard during the analysis of furanic compounds by reversed-phase-high performance liquid chromatography–diode array detection (RP-HPLC–DAD) method. | [General Description]
5-Chloro-2-furaldehyde is also known as 5-chlorofurfural. It reacts with aniline and aniline hydrochloride to form bis-(phenylamino) derivatives, without the furan ring cleavage. It also undergoes coupling with ethyl acetoacetate to form the corresponding ethyl bis-acetoacetate. | [References]
[1] Chemistry - A European Journal, 2016, vol. 22, # 1, p. 129 - 133
[2] Patent: WO2004/33440, 2004, A1. Location in patent: Page 238
[3] Patent: US2004/147559, 2004, A1. Location in patent: Page 121
[4] Patent: US2004/106794, 2004, A1. Location in patent: Page 122
[5] Patent: WO2005/66147, 2005, A1. Location in patent: Page/Page column 207 |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
36/37/38 | [Safety Statements ]
26-36 | [WGK Germany ]
3
| [HS Code ]
29321900 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
|
| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
| Company Name: |
Maya High Purity Chemicals
|
| Telephone: |
+86 (573) 82222445 (0)18006601000 452520369 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList15221/0_EN.htm |
| Company Name: |
Sigma-Aldrich
|
| Telephone: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
|