| Identification | Back Directory | [Name]
CT-1 | [CAS]
2155822-92-5 | [Synonyms]
CT-1
CTF1
CRTR
MGC87396
COF-CTF-1
MAGE-1 human
Cardiophin 1
Antigen MZ2-E
CTF-1/CTF-HUST-1
Cancer/testis antigen 1
Cardiotrophin-1 from mouse
Melanoma-associated antigen 1
Human Cardiotrophin-1 ELISA Kit
Anti-SLC6A8 antibody produced in goat
Recombinant Human Cardiotrophin-1/CTF1 Protein, His Tag
solute carrier family 6 (neurotransmitter transporter, creatine), member 8 | [MDL Number]
MFCD01865988 |
| Hazard Information | Back Directory | [Uses]
Cardiotrophin-1 is from interleukin (IL)-6 family of cytokines. It is mainly present in adipose tissues, osteoclasts and cardiomyocytes. Cardiotrophin-1 works through gp130 (glycoprotein) and the LIFR (LIF receptor). | [Biological Activity]
In adipocytescardiotrophin-1 helps in activating signaling pathways associated with metabolism. It controls energy homeostasisand glucose and lipid metabolism. High levels of cardiotrophin-1 are reported in obesity and metabolic syndrome. Absence of cardiotrophin-1 in mice causes mature-onset obesityinsulin resistance and hypercholesterolemia. In osteoclastsit enhances osteoblast activity as well as mineralization. It also participates in cardiomyocyte survivalhypertrophycardiac fibroblast proliferation and collagen type I synthesis. Cardiotrophin-1 is associated with arterial fibrosis and stiffness. |
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shlmai
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021-67680335 13052188602 |
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www.shlmai.net/ |
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