| Identification | Back Directory | [Name]
3-amino-1-(2-amino-3-hydroxyphenyl)propan-1-one dihydroiodide | [CAS]
2155855-77-7 | [Synonyms]
3-OH-Kynurenamine (dihydroiodide)
3-amino-1-(2-amino-3-hydroxyphenyl)propan-1-one dihydroiodide
1-Propanone, 3-amino-1-(2-amino-3-hydroxyphenyl)-, hydriodide (1:2) |
| Hazard Information | Back Directory | [Uses]
3-OH-Kynurenamine dihydroiodide is the dihydroiodide form of 3-OH-Kynurenamine (HY-156908). 3-OH-Kynurenamine dihydroiodide is an activator for aryl hydrocarbon receptor (AhR), and thus regulates the immune response. 3-OH-Kynurenamine dihydroiodide upregulates the expressions of Ido1 and Tgfb1, ameliorates the skin inflammation in psoriasis mouse model and kidney damage in nephrotoxic lupus mouse model[1]. | [References]
[1] Laura SANTAMBROGIO. Immunoregulatory role of 3-oh-kynurenamine and uses thereof. Patent, WO2019178013A1. |
|
|