| Identification | Back Directory | [Name]
3-(5-Methylisoxazol-3-yl)-6-[(1-methyl-1H-1,2,3-triazol-4-yl)methoxy][1,2,4]triazolo[3,4-a]phthalazine | [CAS]
215874-86-5 | [Synonyms]
α5IA
a5IA
L822
L-822
L 822
L822179
L-822179
L 822179
Α5ia (α5IA)
3-(5-Methylisoxazol-3-yl)-6-[(1-Methyl-1H-1,2,3-triazol-4-yl)Met
5-methyl-3-[6-[(1-methyltriazol-4-yl)methoxy]-[1,2,4]triazolo[3,4-a]phthalazin-3-yl]-1,2-oxazole
3-(5-Methylisoxazol-3-yl)-6-(1-methyl-1,2,3-triazol-4-yl)methoxy-1,2,4-triazolo[3,4-a]phthalazine
3-(5-Methylisoxazol-3-yl)-6-[(1-methyl-1H-1,2,3-triazol-4-yl)methoxy][1,2,4]triazolo[3,4-a]phthalazine
5-Methyl-3-(6-((1-Methyl-1H-1,2,3-triazol-4-yl)Methoxy)-[1,2,4]triazolo[3,4-a]phthalazin-3-yl)isoxazole
1,2,4-Triazolo[3,4-a]phthalazine, 3-(5-methyl-3-isoxazolyl)-6-[(1-methyl-1H-1,2,3-triazol-4-yl)methoxy]- | [Molecular Formula]
C17H14N8O2 | [MDL Number]
MFCD09832717 | [MOL File]
215874-86-5.mol | [Molecular Weight]
362.35 |
| Hazard Information | Back Directory | [Uses]
Alpha5IA is an α5-selective inverse agonist which enhance cognitive performance in rodents and encouraging in human. A triazolophthalazine that selectively attentuates the effects of GABA at GABAA receptors. | [in vivo]
α5IA (5 mg/kg, i.p., once) can sustain restoration of spatial learning ability in Ts65Dn mice, and long-term recognition of spatial memory deficits[2].
|
|
|