| Identification | Back Directory | [Name]
Ethanone, 1-[4-[[3-amino-5-[(4S)-4-amino-2-oxa-8-azaspiro[4.5]dec-8-yl]-2-pyrazinyl]thio]-3,3-difluoro-2,3-dihydro-1H-indol-1-yl]-, hydrochloride (1:1) | [CAS]
2169223-49-6 | [Synonyms]
JAB-3068 hydrochloride
SHP2-IN-6 hydrochloride
Ethanone, 1-[4-[[3-amino-5-[(4S)-4-amino-2-oxa-8-azaspiro[4.5]dec-8-yl]-2-pyrazinyl]thio]-3,3-difluoro-2,3-dihydro-1H-indol-1-yl]-, hydrochloride (1:1) | [Molecular Formula]
C22H27ClF2N6O2S | [MOL File]
2169223-49-6.mol | [Molecular Weight]
513 |
| Hazard Information | Back Directory | [Uses]
JAB-3068 (SHP2-IN-6) hydrochloride is a potent SHP2 inhibitor with an IC50 of 25.8 nM. JAB-3068 hydrochloride is extracted from patent WO2017211303A1, compound 7[1]. | [References]
[1] Cunbo Ma, et al. Novel heterocyclic derivatives useful as shp2 inhibitors. WO2017211303A1. |
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