| Identification | Back Directory | [Name]
1,12-Dodecanedione, 1,12-bis[4-(4-amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]- | [CAS]
2169273-66-7 | [Synonyms]
EphA2 agonist 2
1,12-Dodecanedione, 1,12-bis[4-(4-amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]- | [Molecular Formula]
C40H56N10O6 | [MOL File]
2169273-66-7.mol | [Molecular Weight]
772.94 |
| Hazard Information | Back Directory | [Uses]
EphA2 agonist 2 (Lead compound) is a selective EphA2 agonist with antitumor activities. EphA2 agonist 2 can cross the BBB[1]. | [References]
[1] Orahoske CM, et al. Dimeric small molecule agonists of EphA2 receptor inhibit glioblastoma cell growth. Bioorg Med Chem. 2020 Sep 15;28(18):115656. DOI:10.1016/j.bmc.2020.115656 |
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