ChemicalBook--->CAS DataBase List--->2170347-90-5

2170347-90-5

Request For Quotation
2170347-90-5 Structure

2170347-90-5 Structure
IdentificationBack Directory
[Name]

LSD1-IN-13 hydrochloride
[CAS]

2170347-90-5
[Synonyms]

LSD1-IN-13 hydrochloride
Hazard InformationBack Directory
[Uses]

LSD1-IN-13 hydrochloride (compound 7e) is an orally active and potent LSD1 inhibitor, with an IC50 of 24.43 nM. LSD1-IN-13 hydrochloride can activate CD86 expression, with an EC50 of 470 nM. LSD1-IN-13 hydrochloride induces differentiation of AML (acute myeloid leukemia) cell lines[1].
[in vivo]

LSD1-IN-13 hydrochloride (compound 7e) (MV-4-11 xenograft mice, 0-20 mg/kg, Orally, daily for 15 days) suppresses tumor growth significantly in a dose-dependent manner[1].

[IC 50]

KDM1/LSD1
[References]

[1] Li C, et al. Structure-Activity Relationship Study of Indolin-5-yl-cyclopropanamine Derivatives as Selective Lysine Specific Demethylase 1 (LSD1) Inhibitors. J Med Chem. 2022 Mar 10;65(5):4335-4349. DOI:10.1021/acs.jmedchem.1c02156
2170347-90-5 suppliers list
Company Name: TargetMol Chemicals Inc.  
Telephone: 15002134094
Website: https://www.targetmol.cn/
Tags:2170347-90-5 Related Product Information
5455-89-0 211675-82-0 847171-51-1 312587-72-7