ChemicalBook--->CAS DataBase List--->2170830-26-7

2170830-26-7

2170830-26-7 Structure

2170830-26-7 Structure
IdentificationBack Directory
[Name]

TGFBR1-IN-1
[CAS]

2170830-26-7
[Synonyms]

GFBR1-IN-1
TGFBR1-IN-1
TGFBR1IN1,TGFBR1 IN 1,TGFBR-1-IN-1
1H-Pyrazole-3-carboxamide, 5-(6-benzothiazolyl)-N-(4-hydroxyphenyl)-1-(6-methyl-2-pyridinyl)-
[Molecular Formula]

C23H17N5O2S
[MDL Number]

MFCD32689704
[MOL File]

2170830-26-7.mol
[Molecular Weight]

427.48
Chemical PropertiesBack Directory
[Boiling point ]

636.3±55.0 °C(Predicted)
[density ]

1.43±0.1 g/cm3(Predicted)
[pka]

9.74±0.26(Predicted)
Hazard InformationBack Directory
[Uses]

TGFBR1-IN-1 is an ALK5 inhibitor extracted from patent WO2018004290A1, Compound 33, has an IC50 of 10-100 nM[1].
[IC 50]

ALK5: 10-100 nM (IC50)
[References]

[1] Novel pyrazole derivative as alk5 inhibitor and uses thereof. WO2018004290A1.
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