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2170834-63-4

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2170834-63-4 Structure

2170834-63-4 Structure
IdentificationBack Directory
[Name]

QPX7728
[CAS]

2170834-63-4
[Synonyms]

QPX7728
Xeruborbactam
Benzo[e]cycloprop[c][1,2]oxaborin-4-carboxylic acid, 5-fluoro-1,1a,2,7b-tetrahydro-2-hydroxy-, (1aR,7bS)-
[Molecular Formula]

C10H8BFO4
[MDL Number]

MFCD34470208
[MOL File]

2170834-63-4.mol
[Molecular Weight]

221.98
Chemical PropertiesBack Directory
[Boiling point ]

358.5±52.0 °C(Predicted)
[density ]

1.54±0.1 g/cm3(Predicted)
[pka]

2.30±0.20(Predicted)
Hazard InformationBack Directory
[Uses]

Xeruborbactam (QPX7728) is a potent, ultra-broad-spectrum boronic acid beta-lactamase inhibitor. Xeruborbactam inhibits key serine and metallo beta-lactamases at a nano molar range[1].
[References]

[1] Lomovskaya O, et al, The Impact of Intrinsic Resistance Mechanisms on Potency of QPX7728, a New Ultra-Broad-Spectrum Beta-lactamase Inhibitor of Serine and Metallo Beta-Lactamases in Enterobacteriaceae, Pseudomonas aeruginosa, and Acinetobacter baumannii. DOI:10.1128/AAC.00552-20
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