| Identification | Back Directory | [Name]
CYCLO(-ARG-GLY-ASP-D-TYR-LYS) | [CAS]
217099-14-4 | [Synonyms]
CYCLO(-RGDYK)
cyclo (Arg-Gly-Asp-Tyr-Lys)
CYCLO(-ARG-GLY-ASP-D-TYR-LYS)
Cyclo(-Arg-Gly-Asp-D-Tyr-Lys) trifluoroacetate salt
Cyclo(L-arginylglycyl-L-α-aspartyl-D-tyrosyl-L-lysyl) | [Molecular Formula]
C27H41N9O8 | [MDL Number]
MFCD08459533 | [MOL File]
217099-14-4.mol | [Molecular Weight]
619.67 |
| Chemical Properties | Back Directory | [density ]
1.52±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [form ]
Solid | [pka]
4.01±0.10(Predicted) | [color ]
White to off-white | [Sequence]
Cyclo(Arg-Gly-Asp-{d-Tyr}-Lys) |
| Hazard Information | Back Directory | [Uses]
Cyclo(RGDyK) is a potent and selective αVβ3 integrin inhibitor with an IC50 of 20 nM. | [IC 50]
αvβ3: 20 nM (IC50) | [References]
[1] Haubner R, et al. Glycosylated RGD-containing peptides: tracer for tumor targeting and angiogenesis imaging with improved biokinetics. J Nucl Med. 2001 Feb;42(2):326-36. PMID:11216533 |
|
| Company Name: |
Alabiotech Inc.
|
| Tel: |
001-619-354-5251 |
| Website: |
www.alabiotech-e.com |
|