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GB1490 is an orally active galectin inhibitor with Kd values of 0.4 μM and 2.7 μM for galectin-1 and galectin-3, respectively[1]. | [IC 50]
Galectin-1: 0.4 μM (Kd); Galectin-3: 2.7 μM (Kd) | [References]
[1] Fredrik R Zetterberg, et al. Discovery of Selective and Orally Available Galectin-1 Inhibitors. J Med Chem. 2023 Dec 7. DOI:10.1021/acs.jmedchem.3c01787 |
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