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2173146-34-2

2173146-34-2 Structure

2173146-34-2 Structure
IdentificationBack Directory
[Name]

3-Deshydroxy 3-Keto Saxagliptin
[CAS]

2173146-34-2
[Synonyms]

Saxagliptin Impurity 61
Piraxostat Impurity 35
3-Deshydroxy 3-Keto Saxagliptin
Deshydroxy Saxagliptin Impurity
2-Azabicyclo[3.1.0]hexane-3-carbonitrile, 2-[(2S)-2-amino-2-(4-oxotricyclo[3.3.1.13,7]dec-1-yl)acetyl]-, (1S,3S,5S)-
[Molecular Formula]

C18H23N3O2
[MOL File]

2173146-34-2.mol
[Molecular Weight]

313.39
Chemical PropertiesBack Directory
[Boiling point ]

557.5±35.0 °C(Predicted)
[density ]

1.34±0.1 g/cm3(Predicted)
[pka]

8.13±0.50(Predicted)
Hazard InformationBack Directory
[Uses]

3-Deshydroxy 3-Keto Saxagliptin is a Saxagliptin (S143500) impurity, a potent and selective reversible inhibitor of dipeptidyl peptidase-4, which is being developed for the treatment of type 2 diabetes. It is absorbed rapidly after oral administration and has a pharmacokinetic profile compatible with once daily dosing.
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