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2182601-72-3

2182601-72-3 Structure

2182601-72-3 Structure
IdentificationBack Directory
[Name]

Cy5 DBCO
[CAS]

2182601-72-3
[Synonyms]

[Molecular Formula]

C50H53ClN4O2
[MOL File]

2182601-72-3.mol
[Molecular Weight]

777.45
Chemical PropertiesBack Directory
[InChIKey]

HWIXBRHDYGXXEQ-UHFFFAOYSA-N
[SMILES]

C(N1C(C(C)(C)C2=CC=CC=C12)=CC=CC=CC1C(C2=CC=CC=C2[N+]=1C)(C)C)CCCCC(=O)NCCC(N1CC2=CC=CC=C2C#CC2=CC=CC=C12)=O.[Cl-]
Hazard InformationBack Directory
[Description]

Cy5 DBCO is a linker of the cyanine5 dye. The addition of the DBCO molecule allows for the compound to undergo copper-free Click Chemistry reactions.
[Uses]

Cy5 DBCO chloride is an azide reaction probe and the addition of DBCO molecules allows the imaging of azide-labelled biomolecules by a copper-free "Click Chemistry" reaction[1]. Cy5 DBCO (chloride) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
[References]

[1] Sun-Woong Kang, et al. Cell labeling and tracking method without distorted signals by phagocytosis of macrophages. Theranostics. 2014 Feb 12;4(4):420-31. DOI:10.7150/thno.7265
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