ChemicalBook--->CAS DataBase List--->2187430-05-1

2187430-05-1

2187430-05-1 Structure

2187430-05-1 Structure
IdentificationBack Directory
[Name]

Batoclimab
[CAS]

2187430-05-1
[Synonyms]

Batoclimab
Research Grade Batoclimab(DHF14603)
Chemical PropertiesBack Directory
[form ]

Liquid
[color ]

Colorless to light yellow
Hazard InformationBack Directory
[Uses]

Batoclimab is a fully humanized IgG1 monoclonal antibody targeting FcRn. Batoclimab can be used in the research of autoimmune diseases such as myasthenia gravis and thyroid eye disease[1][2].
[References]

[1] Yan C, et, al. Therapeutic Effects of Batoclimab in Chinese Patients with Generalized Myasthenia Gravis: A Double-Blinded, Randomized, Placebo-Controlled Phase II Study. Neurol Ther. 2022 Apr 12. DOI:10.1007/s40120-022-00345-9
[2] Kahaly GJ, et al. Proof-of-concept and Randomized, Placebo-controlled Trials of an FcRn Inhibitor, Batoclimab, for Thyroid Eye Disease. J Clin Endocrinol Metab. 2023 Nov 17;108(12):3122-3134. DOI:10.1210/clinem/dgad381
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