| Identification | Back Directory | [Name]
IMISOPASEM MANGANESE | [CAS]
218791-21-0 | [Synonyms]
CG4419
CG-4419
SC72325
M-40403
CG 4419
SC-72325
SC 72325
IMISOPASEM MANGANESE
Imisopasem manganese(m40403)
M40403; M 40403; M-40403; CG4419; CG 4419; CG-4419; SC72325; SC-72325; SC 72325; IMISOPASEM MANGANESE | [Molecular Formula]
C21H35N5.Cl2Mn | [MOL File]
218791-21-0.mol | [Molecular Weight]
483.387 |
| Chemical Properties | Back Directory | [storage temp. ]
Inert atmosphere,2-8°C | [solubility ]
DMSO:5.0(Max Conc. mg/mL);10.34(Max Conc. mM)
DMF:3.0(Max Conc. mg/mL);6.21(Max Conc. mM)
Ethanol:20.0(Max Conc. mg/mL);41.38(Max Conc. mM)
PBS (pH 7.2):3.0(Max Conc. mg/mL);6.21(Max Conc. mM)
Water:16.0(Max Conc. mg/mL);33.1(Max Conc. mM) | [form ]
A crystalline solid | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Relief of pain and inflammation. | [in vivo]
Imisopasem manganese is a small-molecule superoxide dismutase mimetic that has shown efficacy in animal model disease states in which superoxide anions are thought to play a key role. Imisopasem manganese inhibits the inflammatory response following the intrapleural injection of carrageenan in rats. All parameters of inflammation are attenuated by Imisopasem manganese except for NOx, PGE2 and IL-10 which remains unaltered[1]. Decreased apoptosis of the large and particularly the small bowel and marked recovery of both lymphoid and hematopoietic tissues occurs in the Imisopasem manganese pre-treated mice. Imisopasem manganese is effective in reducing TBI-induced tissue destruction and has potential as a new radioprotective agent[2]. |
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| Company Name: |
LGM Pharma
|
| Tel: |
1-(800)-881-8210 |
| Website: |
www.lgmpharma.com |
| Company Name: |
BOC Sciences
|
| Tel: |
16314854226 |
| Website: |
www.bocsci.com |
|