| Identification | Back Directory | [Name]
2-AMINO-4-CHLORO-6-NITROTOLUENE | [CAS]
219312-44-4 | [Synonyms]
2-AMINO-4-CHLORO-6-NITROTOLUENE
5-Chloro-2-Methyl-3-nitroaniline
2-amino-4-chloro-7-nitro-toluene
5-chloro-2-methyl-3-nitrobenzenamine
Benzenamine, 5-chloro-2-methyl-3-nitro- | [EINECS(EC#)]
200-258-5 | [Molecular Formula]
C7H7ClN2O2 | [MDL Number]
MFCD01109853 | [MOL File]
219312-44-4.mol | [Molecular Weight]
186.6 |
| Chemical Properties | Back Directory | [Boiling point ]
333.4±37.0 °C(Predicted) | [density ]
1.415±0.06 g/cm3(Predicted) | [storage temp. ]
under inert gas (nitrogen or Argon) at 2–8 °C | [pka]
1.08±0.10(Predicted) | [Appearance]
Yellow to orange Solid |
| Hazard Information | Back Directory | [Synthesis]
4-Iodo-2,6-dinitrotoluene (5.9 g, 23.60 mmol) was used as raw material and dissolved in a solvent mixture of methanol (10 mL) and 1,4-dioxane (5 mL). Under ice bath cooling conditions, 10 N hydrochloric acid (12 mL) and iron powder (3.96 g, 70.80 mmol) were slowly added. The reaction mixture was stirred at 80 °C for 3 h. The progress of the reaction was monitored by thin layer chromatography (TLC) until complete conversion of the feedstock. Upon completion of the reaction, 3.55 g of the light yellow powdery product 2-amino-4-chloro-6-nitrotoluene was obtained in 68.4% yield. | [References]
[1] Patent: CN108689937, 2018, A. Location in patent: Paragraph 0069; 0070; 0073; 0074
[2] Patent: CN108689936, 2018, A. Location in patent: Paragraph 0070; 0072; 0076; 0077
[3] Patent: US2010/63066, 2010, A1. Location in patent: Page/Page column 36
[4] Journal of the Chemical Society, 1905, vol. 87, p. 1265
[5] Patent: US5952362, 1999, A |
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