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2200274-63-9

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2200274-63-9 Structure

2200274-63-9 Structure
IdentificationBack Directory
[Name]

Glucagon receptor antagonists-5
[CAS]

2200274-63-9
[Synonyms]

Glucagon receptor antagonists-5
Glucagon receptor antagonists 5,Glucagon receptor antagonists5
β-Alanine, N-[4-[(1S)-1-[5-[2-chloro-4-(trifluoromethyl)phenyl]-6-methyl-1H-indazol-1-yl]-3-methylbutyl]benzoyl]-
[Molecular Formula]

C30H29ClF3N3O3
[MDL Number]

MFCD32263035
[MOL File]

2200274-63-9.mol
[Molecular Weight]

572.02
Chemical PropertiesBack Directory
[Boiling point ]

695.2±55.0 °C(Predicted)
[density ]

1.31±0.1 g/cm3(Predicted)
[pka]

4.29±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

Glucagon receptor antagonist-5 (compound 13K) is a potent and orally bioavailable indazole-based glucagon receptor antagonist (Ki=32?nM). Glucagon receptor antagonist-5 has potential for the treatment of type 2 diabetes mellitus (T2DM)[1].
[References]

[1] Xu G, et al. Discovery of potent and orally bioavailable indazole-based glucagon receptor antagonists for the treatment of type 2 diabetes. Bioorg Med Chem Lett. 2019 Oct 15;29(20):126668. DOI:10.1016/j.bmcl.2019.126668
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Company Name: TargetMol Chemicals Inc.
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Website: https://www.targetmol.com/
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354;
Website: https://www.targetmol.com/
Company Name: TargetMol Chemicals Inc.
Tel: +17819995354 , +17819995354
Website:
Company Name: TargetMol Chemicals Inc.  
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Website: https://www.targetmol.cn/
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