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220475-76-3

220475-76-3 Structure

220475-76-3 Structure
IdentificationBack Directory
[Name]

1,4-Benzodioxin-2-carboxylic acid, 6-[(2R)-2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]propyl]-2,3-dihydro-, (2R)-
[CAS]

220475-76-3
[Synonyms]

N5984
N 5984
N-5984
KRP204
KRP-204
KRP 204
1,4-Benzodioxin-2-carboxylic acid, 6-[(2R)-2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]propyl]-2,3-dihydro-, (2R)-
[Molecular Formula]

C20H22ClNO5
[MDL Number]

MFCD11040816
[MOL File]

220475-76-3.mol
[Molecular Weight]

391.85
Chemical PropertiesBack Directory
[Boiling point ]

611.6±55.0 °C(Predicted)
[density ]

1.337±0.06 g/cm3(Predicted)
[pka]

2.65±0.20(Predicted)
Hazard InformationBack Directory
[Uses]

N-5984 (KRP-204) is a potent and selective agonist of β3-adrenergic receptor. N-5984 has the potential for developing as one of the clinically effective drugs for obesity and diabetes mellitus[1].
[IC 50]

β-adrenoceptor
[References]

[1] Yanagisawa T, et al. Selectivity and potency of agonists for the three subtypes of cloned human beta-adrenoceptors expressed in Chinese hamster ovary cells. Tohoku J Exp Med. 2000;192(3):181-193. DOI:10.1620/tjem.192.181
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