ChemicalBook--->CAS DataBase List--->220749-41-7

220749-41-7

220749-41-7 Structure

220749-41-7 Structure
IdentificationBack Directory
[Name]

Cdk1 Inhibitor
[CAS]

220749-41-7
[Synonyms]

Cdk1 Inhbitor
Cdk1 Inhibitor
[Molecular Formula]

C17H11ClN2O
[MOL File]

220749-41-7.mol
[Molecular Weight]

294.73
Chemical PropertiesBack Directory
[Boiling point ]

585.1±50.0 °C(Predicted)
[density ]

1.450±0.06 g/cm3(Predicted)
[solubility ]

DMSO: soluble
[form ]

A solid
[pka]

11.94±0.20(Predicted)
[color ]

White to yellow
Hazard InformationBack Directory
[Description]

QLN49417, also known as CDK1 inhibitor 8a, is a selective CDK1 inhibitor. This compound was first reported by Andreani, Aldo; et al in Anti-Cancer Drug Design (2001), 15(6), 447-452. This product has no formal name at the moment.
[Uses]

CDK1-IN-2 is a CDK1 inhibitor (IC50: 5.8 μM)[1].
[IC 50]

CDK1: 5.8 μM (IC50)
[References]

[1] Jorda R, et al. How Selective Are Pharmacological Inhibitors of Cell-Cycle-Regulating Cyclin-Dependent Kinases? J Med Chem. 2018 Oct 25;61(20):9105-9120. DOI:10.1021/acs.jmedchem.8b00049
Spectrum DetailBack Directory
[Spectrum Detail]

Cdk1 Inhibitor(220749-41-7)1HNMR
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