| Identification | Back Directory | [Name]
1-(2,5-Dihydroxy-4-methoxyphenyl)ethanone | [CAS]
22089-12-9 | [Synonyms]
1-(2,5-Dihydroxy-4-methoxyphenyl)ethanone
Ethanone, 1-(2,5-dihydroxy-4-methoxyphenyl)- | [Molecular Formula]
C9H10O4 | [MDL Number]
MFCD00597670 | [MOL File]
22089-12-9.mol | [Molecular Weight]
182.17 |
| Hazard Information | Back Directory | [Uses]
2,5-Dihydroxy-4-methoxyacetophenone (compounds 3) can be isolated from the 80% methanol extract of roots of Cynanchum paniculatum Kitagawa. 2,5-Dihydroxy-4-methoxyacetophenone inhibits glutamate-induced cytotoxicity in hippocampal HT22 cell line[1]. | [Preparation]
Preparation by Fries rearrangement of 2-methoxyhydroquinone diacetate, ? with boron trifluoride in acetic acid (97%); ? with aluminium chloride in nitrobenzene at r.t., (38%). | [References]
[1] Jin Bae Weon, et al. Neuroprotective compounds isolated from Cynanchum paniculatum. Arch Pharm Res. 2012, 35, 4. DOI:10.1007/s12272-012-0404-4 |
|
|